(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways
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چکیده
منابع مشابه
(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways
OBJECTIVE In the wake of intracerebral hemorrhage (ICH), a devastating stroke with no effective treatment, hemoglobin/iron-induced oxidative injury leads to neuronal loss and poor neurologic outcomes. (-)-Epicatechin (EC), a brain-permeable flavanol that modulates redox/oxidative stress via the NF-E2-related factor (Nrf) 2 pathway, has been shown to be beneficial for vascular and cognitive func...
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ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2014
ISSN: 2328-9503
DOI: 10.1002/acn3.54